Description
(Natural multifunctional antibiotic, antibacterial, antiviral and antifungal)
Composition:
Antibiofish is a pure natural drug composed of highly potent therapeutic herbs such as Thyme (Thymus vulgaris) and Ajowan (Trachyspermum ammi) and few other herbs. The most important constituents in the drug enolic compounds such as Thymol, Carvacrol, Paracymol and Cineole.
MECHANISM OF ACTION:
Antibiofish contains a large amount of terpenoid phenols such as Thymol and Convacrol. The natural substance; Thymol is now accepted in the EU standards as an effective antimicrobial agent but harmless for humans. Both Thymol and Carvacrol are classified as monoterpenoids, since they have a carbon ring and oxygen (hydroxyl group) functionality. Evidences such as the images of the electron microscope have shown that these two monoterpenoids can be directly enclosed within the cell wall of the bacteria and, by disrupting its structure, increase the permeability of the cell wall of the bacterium.
The Thymol and Carvacrol molecules are lipophilic and also have a small molecular size. They are almost similar but the only difference is the location of hydroxyl group on the hexagonal carbon ring. This structural difference makes the thymol more hydrophobic and Carvacrol more biologically active. Hydrophobic and lipophilic nature of the both molecules makes them very prone to be absorbed into the bacterial cellular membrane which is made of two-layer phospholipids. As a result. Thymol and Carvacrol can disrupt the structural order of the membrane (i.e. alteration of membrane fatty acids). Thus, the replacement of Thymol and Carvacrol into the cell membrane of the bacteria will mess up the regular structure of the membrane components, and the fatty acids will separate from the membrane. Following these changes and damage to the cell membrane, vital intracellular contents of the bacterial cell such as the metabolites and ions leak out of the damaged membrane. By the direct effect of Thymol and Carvacrol on bacterial cell wall proteins and molecules, shrinkage and coagulation in the bacterial wall will occur and lead bacteria to die.
The most important and deadly effect of Thymol and Carvacrol on bacterial cell wall is their capability to create pores in the membrane structure, which causes the leakage of vital substances from the bacterial cell due to a much higher osmotic pressure within the bacterial cell than the pressure in extracellular matrix. According to recent knowledge, natural antibiotics such as Thymol and Carvacrol have proven antimicrobial effects, and the drugs based on these compounds can prevent the development of various types of infectious diseases. In addition, Antibiofish not only can protect the fish from internal/systemic infectious diseases but also can disinfect the environmental water where the fish were cultured. By disinfecting the water, the drug can also protect the fish from dermal infectious diseases.
THERAPEUTIC FEATURES: active substances of Antibiofish inhibit the growth and proliferation of bacteria and pathogenic fungi, particularly in the gastrointestinal tract and the dermal surfaces. These substances physically manipulate the structure of bacterial cell wall and therefore do not induce drug resistance in bacteria, so the drug can be used to prevent diseases in an optimal way. It can also show a synergistic effect when accompanied with other antibiotics to prevent the progression of the diseases.
INDICATIONS:
- Prevention and treatment of gastrointestinal tract and dermal infections without emergence of drug-resistance and reducing the recovery time.
- Prevention of the progression of the infectious diseases (without interrupting other drugs function, no contraindications).
- Acts as an effective growth promoter.
- As a water disinfectant can be used in fish farming pools.
TARGET ANIMALS: Fish.
INSTRUCTIONS TO USE: 1. For the prevention of bacterial diseases, please mix 100 ml of the drug in 100 kg of the feed. 2. For the prevention of fungal diseases, please mix 2 liters of the drug in 1000 liters of the pool water.
CONTRAINDICATIONS: Should not be used at the vaccination time.
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