( mycotoxin-binder/absorbent for poultry )
COMPOSITION: Mycotoxifin is a unique toxin binder, based on latest advances with an optimized formulation for use in poultry nutrition. The Mycotoxifin has been made using the state of the art technology of toxin-binders. For this purpose, special attention has been paid to the physiology of the gastrointestinal tract, the range of effects of each component of the drug, as well as the pathologic effects of mycotoxin-contamination in the nutrition of the birds New approaches to formulate the toxin binder (Mycotoxifin) and the use of therapeutic active ingredients from medicinal plants (i.e. thyme, peppermint and few other herbs) along with other components such as minerals and yeast cell wall have resulted in increased efficacy and multi-dimensional effects in final product (Mycotoxifin), such as toxin absorption, toxin degradation, toxin blocking and healing/repairing of the damaged intestinal tissue, thus providing a unique product. In the manufacturing processes of the product, we used ingredients with passed EU standards and special carriers which protects the ingredients and maintains the quality of the product for a long time (increased shelf life) and increases the efficacy of the components. The carrier has nutritional value and therefore can also act as a nutritional supplement for the birds and improves the growth and performance.
MECHANISM OF ACTION:
Viable yeast: The biologically active and non-pathogen yeast, as a probiotic, can produce and release esterase, an enzyme which can transform mycotoxins and make the active groups o mycotoxins to be harmless (catalyzes or deactivates the active groups) within the digestive tract. The esterase and few other types of enzyme within the Mycotoxifin can transform the fumonisins and other types of mycotoxins to less toxic and even up to harmless molecules Moreover, the yeast growth and proliferation in the intestine restricts the suitable mucosal area for the proliferation of harmful microorganisms and makes the nutritional molecules inaccessible for the microbes. Thus, Mycotoxifin acts as a really effective probiotic and a growth stimulant.
Chemically engineered clays: We have incorporated one unique, modified clay (patented), which is loaded with magnesium and potassium instead of conventional clays loaded with calcium and sodium. It has an enhanced mycotoxin absorption capacity (particularly polar ones) of about 12 times more than that by conventional organic absorbents (unmodified, intact clays).
Medicinal herbal ingredients: There are four pathways forming the molecular basis of anti-mycotoxin effects of herbal active ingredients of Mycotoxifin as followings: 1) prevention of the toxic and harmful effects of mycotoxins on the liver tissue (hepato-protective and inhibition of hepatotoxicity of mycotoxins), 2) inhibition of severe inflammatory responses, reducing the cytokine (e.g. IL-6 and tumor necrosis factor-a) production, 3) the antioxidant effect; limiting the oxidative stress by inducing the glutathione peroxidase (i.e. controls the oxidative stress) and inhibiting the production of harmful malondialdehyde, and 4) these herbal substances can accelerate the healing process of mucosal scars/wounds caused by mycotoxins. The mucosal injuries can be cured rapidly by the herbal active ingredients within the Mycotoxifin. These molecules have strong stimulatory effects on production, formation and rearrangement of collagens/fibrins (i.e. constitute the connective tissue) and fibroblasts.
Organic acids: Humic acids (HAs) are produced through biological/chemical reactions; during the process of humifying the organic matter of the soil (humus) which is a result of biological activity of various microorganisms. In fact, HAS are consisted of a mixture of partially and totally humified soil compounds. Therefore, HAs do not have a specific structure but are composed of several intermediate structures, mostly oxidized with negative charge. This combination of diverse structures can trap the mycotoxins as a result of their specific structural features and the negative charge, and then excrete the trapped mycotoxins from the gastrointestinal tract.
THERAPEUTIC FEATURES: Absorption/degradation of polar and non-polar mycotoxins, hepato-protective, regulation of immune function by herbal compounds, stimulating the immune response by yeast cell wall fragments, boosting healing process of mucosal wounds/injuries (i.e. formed due to histopathology of mycotoxins), prevent mold growth, prevent bacterial growth, anti-oxidant properties due to blocking the formation of free radicals.
INDICATIONS: For the feed/diet/concentrate which is suspected for mold growth or mycotoxin contamination, birds showing sub-acute/chronic clinical/post-mortem symptoms of mycotoxin damages, for prevention of mold growth in feed, for prevention of mycotoxins harmful effects
TARGET ANIMALS: It can be administered for a variety of birds, including chicken, turkey, quail, partridge, and others.
INSTRUCTIONS TO USE:
- Broilers: please mix 1-2 kg per ton diet.
- Laying hens: please mix 0.5-1 kg per ton diet.
- Breeders (mother hens): please mix 0.5-1 kg per ton diet.
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